One bad apple can spoil the rest so please remove them from the basket.
As a leader you must establish, promote and support an inviting, comfortable and respectful working environment and as such you can’t allow any single individual to jeopardize your workplace. No matter how good and valuable they may be from a functional perspective if they can’t cooperate and collaborate professionally it is your leadership responsibility to step in and have it addressed.
Fortunately, in most environments, these types of issues are rare and far apart, but should they occur their impact can’t be underestimated and they must be resolved immediately.